STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JMJD1CJumonji domain containing 1C. (2545 aa)    
Predicted Functional Partners:
NIPBL
Nipped-B protein.
   
  
 0.739
GPR149
G protein-coupled receptor 149.
      
 0.697
XXYLT1
Xyloside xylosyltransferase 1.
      
 0.677
REEP3
Receptor expression-enhancing protein.
 
 
  
 0.665
R3HCC1
R3H domain and coiled-coil containing 1.
      
 0.629
KDM7A
Lysine demethylase 7A.
   
  
 0.612
SETD1A
SET domain containing 1A, histone lysine methyltransferase.
   
 
 0.587
BAZ2B
Bromodomain adjacent to zinc finger domain 2B.
   
  
 0.564
MED9
Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.558
INTS11
Integrator complex subunit 11.
      
 0.545
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.