node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKAP10 | LOC476208 | ENSCAFP00000026745 | ENSCAFP00000048886 | A-kinase anchoring protein 10. | Uncharacterized protein. | 0.676 |
APOB | CFTR | ENSCAFP00000005806 | ENSCAFP00000005112 | Apolipoprotein B. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.581 |
APOB | LOC476208 | ENSCAFP00000005806 | ENSCAFP00000048886 | Apolipoprotein B. | Uncharacterized protein. | 0.511 |
APOB | SCARB1 | ENSCAFP00000005806 | ENSCAFP00000057688 | Apolipoprotein B. | Scavenger receptor class B member 1; Belongs to the CD36 family. | 0.909 |
CFTR | APOB | ENSCAFP00000005112 | ENSCAFP00000005806 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Apolipoprotein B. | 0.581 |
CFTR | EZR | ENSCAFP00000005112 | ENSCAFP00000000937 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | FERM domain-containing protein. | 0.651 |
CFTR | LOC476208 | ENSCAFP00000005112 | ENSCAFP00000048886 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Uncharacterized protein. | 0.536 |
CUBN | LOC476208 | ENSCAFP00000006833 | ENSCAFP00000048886 | Cubilin; Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal t [...] | Uncharacterized protein. | 0.534 |
CUBN | SLC17A1 | ENSCAFP00000006833 | ENSCAFP00000015622 | Cubilin; Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal t [...] | Solute carrier family 17 member 1. | 0.728 |
CUBN | SLC3A1 | ENSCAFP00000006833 | ENSCAFP00000003699 | Cubilin; Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal t [...] | Solute carrier family 3 member 1. | 0.524 |
EZR | CFTR | ENSCAFP00000000937 | ENSCAFP00000005112 | FERM domain-containing protein. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.651 |
EZR | LOC476208 | ENSCAFP00000000937 | ENSCAFP00000048886 | FERM domain-containing protein. | Uncharacterized protein. | 0.521 |
LOC476208 | AKAP10 | ENSCAFP00000048886 | ENSCAFP00000026745 | Uncharacterized protein. | A-kinase anchoring protein 10. | 0.676 |
LOC476208 | APOB | ENSCAFP00000048886 | ENSCAFP00000005806 | Uncharacterized protein. | Apolipoprotein B. | 0.511 |
LOC476208 | CFTR | ENSCAFP00000048886 | ENSCAFP00000005112 | Uncharacterized protein. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.536 |
LOC476208 | CUBN | ENSCAFP00000048886 | ENSCAFP00000006833 | Uncharacterized protein. | Cubilin; Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal t [...] | 0.534 |
LOC476208 | EZR | ENSCAFP00000048886 | ENSCAFP00000000937 | Uncharacterized protein. | FERM domain-containing protein. | 0.521 |
LOC476208 | LOC610380 | ENSCAFP00000048886 | ENSCAFP00000020012 | Uncharacterized protein. | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. | 0.507 |
LOC476208 | SCARB1 | ENSCAFP00000048886 | ENSCAFP00000057688 | Uncharacterized protein. | Scavenger receptor class B member 1; Belongs to the CD36 family. | 0.589 |
LOC476208 | SLC17A1 | ENSCAFP00000048886 | ENSCAFP00000015622 | Uncharacterized protein. | Solute carrier family 17 member 1. | 0.673 |