STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIF13BKinesin family member 13B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2104 aa)    
Predicted Functional Partners:
LOC102151505
PH domain-containing protein.
 
 
 
 0.783
LOC492026
Uncharacterized protein.
      
 0.676
LOC609814
Nuclear RNA export factor 2.
      
 0.676
ADAP2
ArfGAP with dual PH domains 2.
   
 
 0.605
ADAP1
ArfGAP with dual PH domains 1.
    
 
 0.598
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
    
 
 0.590
KIFC2
Kinesin family member C2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
0.581
STX18
Syntaxin 18.
   
 
 0.525
ARF4
ADP ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family.
    
 0.525
RAB25
Ras-related protein Rab-25; Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
    
 
 0.522
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.