STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM189A1Family with sequence similarity 189 member A1. (604 aa)    
Predicted Functional Partners:
IQCA1L
IQ motif containing with AAA domain 1 like.
      
 0.859
N4BP1
NEDD4 binding protein 1.
    
 
 0.763
RNF212
Ring finger protein 212.
      
 0.675
NDFIP2
Nedd4 family interacting protein 2.
   
  
 0.652
NDFIP1
Nedd4 family interacting protein 1.
   
  
 0.649
ITCH
E3 ubiquitin-protein ligase.
    
 
 0.596
FGFRL1
Fibroblast growth factor receptor like 1.
      
 0.538
ZNF461
Zinc finger protein 461.
    
 
 0.525
SLTM
SAFB like transcription modulator.
   
  
 0.503
CCDC61
Coiled-coil domain containing 61.
      
 0.503
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.