STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LETM1Leucine zipper and EF-hand containing transmembrane protein 1. (765 aa)    
Predicted Functional Partners:
C1QBP
Complement C1q binding protein.
   
  
 0.729
FAM53A
Family with sequence similarity 53 member A.
      
 0.718
TMEM11
Transmembrane protein 11.
   
  
 0.700
MICU1
Mitochondrial calcium uptake 1.
      
 0.661
RPS7
40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.
    
 
 0.654
MICU2
Mitochondrial calcium uptake 2.
      
 0.602
MCU
Mitochondrial calcium uniporter.
      
 0.574
PDP2
Pyruvate dehyrogenase phosphatase catalytic subunit 2.
   
  
 0.573
MPHOSPH9
M-phase phosphoprotein 9.
      
 0.570
TMEM129
Transmembrane protein 129.
      
 0.570
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.