STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEK4NIMA related kinase 4. (882 aa)    
Predicted Functional Partners:
CNOT8
CCR4-NOT transcription complex subunit 8.
   
  
 0.808
UIMC1
Ubiquitin interaction motif containing 1.
      
 0.745
SPATA7
Spermatogenesis associated 7.
   
 
 0.732
ZFYVE26
Zinc finger FYVE-type containing 26.
   
  
 0.679
RPGRIP1L
RPGRIP1 like.
   
 
 0.678
FBH1
F-box DNA helicase 1.
   
  
 0.676
PLA2R1
Phospholipase A2 receptor 1.
    
 
 0.676
BEND2
BEN domain containing 2.
      
 0.672
MCM10
Minichromosome maintenance 10 replication initiation factor.
   
 
 0.658
NPHP4
Nephrocystin 4.
   
 
 0.633
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.