STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C8AComplement C8 alpha chain. (608 aa)    
Predicted Functional Partners:
C8G
Complement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family.
   
 0.981
C8B
Complement C8 beta chain.
  
0.955
CNST
Consortin, connexin sorting protein.
      
 0.872
F13B
Coagulation factor XIII B chain.
   
  
 0.774
C9
Complement C9.
   
0.762
C4BPB
Complement component 4 binding protein beta.
   
  
 0.744
FGL1
Fibrinogen like 1.
   
  
 0.707
C1S
Complement C1s; Belongs to the peptidase S1 family.
   
  
 0.671
CFHR5
Complement factor H related 5.
   
  
 0.670
MASP2
Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family.
   
  
 0.667
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.