HDAC6 protein (Canis lupus familiaris) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

HDAC6

Histone deacetylase 6. (1186 aa)

Predicted Functional Partners:

CTTN

0.904

HCLS1

0.874

UBB

0.837

RPS27A

0.825

ENSCAFP00000050780

0.825

SQSTM1

0.798

HDAC11

0.774

NCOR2

0.764

HDAC8

0.762

MAPT

0.762

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTTN	HDAC6	ENSCAFP00000050998	ENSCAFP00000049288	Cortactin.	Histone deacetylase 6.	0.904
ENSCAFP00000050780	HDAC6	ENSCAFP00000050780	ENSCAFP00000049288	Ubiquitin-like domain-containing protein.	Histone deacetylase 6.	0.825
ENSCAFP00000050780	RPS27A	ENSCAFP00000050780	ENSCAFP00000031429	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.405
ENSCAFP00000050780	SQSTM1	ENSCAFP00000050780	ENSCAFP00000065910	Ubiquitin-like domain-containing protein.	Sequestosome 1.	0.745
ENSCAFP00000050780	UBB	ENSCAFP00000050780	ENSCAFP00000063279	Ubiquitin-like domain-containing protein.	Ubiquitin B.	0.986
HCLS1	HDAC6	ENSCAFP00000017015	ENSCAFP00000049288	Hematopoietic cell-specific Lyn substrate 1.	Histone deacetylase 6.	0.874
HDAC11	HDAC6	ENSCAFP00000056345	ENSCAFP00000049288	Histone deacetylase 11.	Histone deacetylase 6.	0.774
HDAC11	HDAC8	ENSCAFP00000056345	ENSCAFP00000040790	Histone deacetylase 11.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.789
HDAC11	NCOR2	ENSCAFP00000056345	ENSCAFP00000010374	Histone deacetylase 11.	Nuclear receptor corepressor 2.	0.751
HDAC6	CTTN	ENSCAFP00000049288	ENSCAFP00000050998	Histone deacetylase 6.	Cortactin.	0.904
HDAC6	ENSCAFP00000050780	ENSCAFP00000049288	ENSCAFP00000050780	Histone deacetylase 6.	Ubiquitin-like domain-containing protein.	0.825
HDAC6	HCLS1	ENSCAFP00000049288	ENSCAFP00000017015	Histone deacetylase 6.	Hematopoietic cell-specific Lyn substrate 1.	0.874
HDAC6	HDAC11	ENSCAFP00000049288	ENSCAFP00000056345	Histone deacetylase 6.	Histone deacetylase 11.	0.774
HDAC6	HDAC8	ENSCAFP00000049288	ENSCAFP00000040790	Histone deacetylase 6.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.762
HDAC6	MAPT	ENSCAFP00000049288	ENSCAFP00000046670	Histone deacetylase 6.	Microtubule-associated protein.	0.762
HDAC6	NCOR2	ENSCAFP00000049288	ENSCAFP00000010374	Histone deacetylase 6.	Nuclear receptor corepressor 2.	0.764
HDAC6	RPS27A	ENSCAFP00000049288	ENSCAFP00000031429	Histone deacetylase 6.	Ubiquitin-like domain-containing protein.	0.825
HDAC6	SQSTM1	ENSCAFP00000049288	ENSCAFP00000065910	Histone deacetylase 6.	Sequestosome 1.	0.798
HDAC6	UBB	ENSCAFP00000049288	ENSCAFP00000063279	Histone deacetylase 6.	Ubiquitin B.	0.837
HDAC8	HDAC11	ENSCAFP00000040790	ENSCAFP00000056345	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 11.	0.789