STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF15Rho guanine nucleotide exchange factor 15. (885 aa)    
Predicted Functional Partners:
ECT2L
Epithelial cell transforming 2 like.
      
 0.792
FGD5
FYVE, RhoGEF and PH domain containing 5.
   
  
 0.720
SH2D5
SH2 domain containing 5.
      
 0.515
LRRC58
Leucine rich repeat containing 58.
      
 0.514
MASP1
Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family.
      
 0.513
CASKIN2
CASK interacting protein 2.
   
  
 0.503
BEND6
BEN domain containing 6.
      
 0.493
RHOC
Uncharacterized protein.
   
 0.493
FBXL12
F-box and leucine rich repeat protein 12.
      
 0.489
BAIAP2
BAI1 associated protein 2.
   
  
 0.488
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.