STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAFP00000049628AGC-kinase C-terminal domain-containing protein. (66 aa)    
Predicted Functional Partners:
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 
 0.781
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 
 0.718
RICTOR
RPTOR independent companion of MTOR complex 2.
    
 
 0.682
PDPK1
3-phosphoinositide dependent protein kinase 1.
    
 
 0.625
TSC2
TSC complex subunit 2.
    
 
 0.613
RHEB
Ras homolog, mTORC1 binding.
   
 
 0.581
ATP5F1D
ATP synthase F1 subunit delta.
   
 
 0.564
MAPKAP1
MAPK associated protein 1.
    
 
 0.560
ATP5F1C
ATP synthase subunit gamma.
   
 
 0.555
EIF4E1B
Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family.
   
 
 0.533
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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