STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ROBO3Roundabout guidance receptor 3. (1421 aa)    
Predicted Functional Partners:
NELL2
Neural EGFL like 2.
    
 
 0.988
NELL1
Neural EGFL like 1.
    
 
 0.980
ROBO1
Roundabout guidance receptor 1.
  
 
0.913
AKAP5
A-kinase anchoring protein 5.
     
 0.903
SLIT1
Slit guidance ligand 1.
    
 
 0.607
SLIT2
Slit guidance ligand 2.
    
 
 0.604
SLIT3
Slit guidance ligand 3.
    
 
 0.533
PRKCA
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 
 0.510
ACIN1
Apoptotic chromatin condensation inducer 1.
      
 0.493
SEMA6B
Semaphorin 6B; Belongs to the semaphorin family.
   
 
 0.485
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.