STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LDHDLactate dehydrogenase D. (498 aa)    
Predicted Functional Partners:
PKLR
Pyruvate kinase PKLR; Plays a key role in glycolysis; Belongs to the pyruvate kinase family.
   
 0.938
PKM
Multifunctional fusion protein; Belongs to the pyruvate kinase family.
    
 0.938
HAGH
Hydroxyacylglutathione hydrolase.
  
 
 0.935
ME1
Malic enzyme.
  
 
 0.919
PDHA1
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.919
ME2
Malic enzyme.
  
 
 0.918
ME3
Malic enzyme.
  
 
 0.918
ENSCAFP00000047270
Ldh_1_N domain-containing protein.
   
 
 0.916
LDHA
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 
 0.916
LDHC
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 
 0.916
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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