STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGD5FYVE, RhoGEF and PH domain containing 5. (1501 aa)    
Predicted Functional Partners:
ARHGEF15
Rho guanine nucleotide exchange factor 15.
   
  
 0.720
ECT2L
Epithelial cell transforming 2 like.
      
 0.682
ARHGEF7
Rho guanine nucleotide exchange factor 7.
   
  
 0.641
USHBP1
USH1 protein network component harmonin binding protein 1.
   
  
 0.606
ARHGEF38
Rho guanine nucleotide exchange factor 38.
      
 0.573
RBM19
RNA binding motif protein 19.
      
 0.562
ARHGEF16
Rho guanine nucleotide exchange factor 16.
   
  
 0.561
RHOJ
Ras homolog family member J.
   
 
 0.548
RBM45
RNA binding motif protein 45.
      
 0.522
DOCK11
Dedicator of cytokinesis 11; Belongs to the DOCK family.
   
 
 0.516
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.