STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NR0B1Nuclear receptor subfamily 0 group B member 1. (487 aa)    
Predicted Functional Partners:
NR6A1
Nuclear receptor subfamily 5 group A member 1.
    
 0.977
ESRRB
Estrogen related receptor beta.
    
 
 0.791
NR5A2
Nuclear receptor subfamily 5 group A member 2.
    
 
 0.725
PRDM14
PR/SET domain 14.
   
 
 0.701
NCOR2
Nuclear receptor corepressor 2.
    
 0.675
NANOG
Homeobox domain-containing protein.
   
 
 0.661
NCOR1
Nuclear receptor corepressor 1.
    
 0.644
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.622
ENSCAFP00000058542
Uncharacterized protein.
   
 
 0.610
FBXO15
F-box protein 15.
   
 
 0.608
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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