STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSBPL9Oxysterol-binding protein; Belongs to the OSBP family. (771 aa)    
Predicted Functional Partners:
STXBP5
Syntaxin binding protein 5.
   
  
 0.878
IFRD2
Interferon related developmental regulator 2.
      
 0.806
SP110
SP110 nuclear body protein.
      
 0.775
PTDSS1
Phosphatidylserine synthase 1.
   
  
 0.769
GFM2
Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
      
 0.752
SH3RF1
SH3 domain containing ring finger 1.
   
  
 0.719
COL4A4
Collagen type IV alpha 4 chain.
      
 0.707
PTPN22
Protein tyrosine phosphatase non-receptor type 22.
      
 0.690
WDR36
WD repeat domain 36.
   
  
 0.682
KHDRBS2
KH RNA binding domain containing, signal transduction associated 2.
   
  
 0.679
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.