STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LACTB2Lactamase beta 2. (401 aa)    
Predicted Functional Partners:
PLA2G12B
Phospholipase A2 group XIIB.
   
  
 0.722
RNASEH1
Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
  
 0.692
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.691
SLC16A9
Solute carrier family 16 member 9.
   
  
 0.687
YBEY
YbeY metalloendoribonuclease.
  
 
 0.639
MKNK2
MAPK interacting serine/threonine kinase 2.
   
  
 0.573
ENSCAFP00000059919
Uncharacterized protein.
   
  
 0.573
RING1
E3 ubiquitin-protein ligase RING1; Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG P [...]
      
 0.563
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
  
  
 0.557
GLOD4
Glyoxalase domain containing 4.
  
 
 0.555
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.