STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKAA1Non-specific serine/threonine protein kinase. (573 aa)    
Predicted Functional Partners:
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
   
 0.999
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
   
 0.999
PRKAG1
Protein kinase AMP-activated non-catalytic subunit gamma 1.
   
 0.995
PRKAG2
Protein kinase AMP-activated non-catalytic subunit gamma 2.
   
 0.985
PRKAG3
Protein kinase AMP-activated non-catalytic subunit gamma 3.
   
 0.982
STK11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
   
0.955
TSC2
TSC complex subunit 2.
   
 0.942
PRKAA2
Non-specific serine/threonine protein kinase.
  
0.938
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 0.935
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
   
0.931
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.