STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFC2Replication factor C subunit 2. (367 aa)    
Predicted Functional Partners:
RFC4
Replication factor C subunit 4.
  
0.999
RFC3
Replication factor C subunit 3.
   
0.998
RFC5
Replication factor C subunit 5.
   
0.998
RAD17
RAD17 checkpoint clamp loader component.
   
 0.997
RFC1
Replication factor C subunit 1.
   
 0.995
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.991
CHTF18
Chromosome transmission fidelity factor 18.
   
 0.966
ATAD5
ATPase family AAA domain containing 5.
   
 
 0.962
HUS1
HUS1 checkpoint clamp component.
   
 0.961
RAD9A
Cell cycle checkpoint control protein; Belongs to the rad9 family.
   
 0.939
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.