STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHPRHSNF2 histone linker PHD RING helicase. (1759 aa)    
Predicted Functional Partners:
PGM2
Phosphoglucomutase 2.
   
    0.820
RAD18
RAD18 E3 ubiquitin protein ligase.
    
 0.808
PHTF2
Putative homeodomain transcription factor 2.
    
 
 0.804
ARID3B
AT-rich interaction domain 3B.
   
 
 0.749
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 
 0.725
UBE2V2
Ubiquitin conjugating enzyme E2 V2.
    
 0.704
YOD1
YOD1 deubiquitinase.
      
 0.677
FANCM
FA complementation group M.
    
 
 0.676
FIGN
Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.
    
 
 0.673
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.672
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.