STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1029 aa)    
Predicted Functional Partners:
FLT3LG
Fms related tyrosine kinase 3 ligand.
   
 0.968
STAT3
Signal transducer and activator of transcription.
   
 0.949
GRB2
Growth factor receptor bound protein 2.
   
 0.948
CEBPA
BZIP domain-containing protein.
     
 0.944
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.943
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.936
PIK3R3
Uncharacterized protein.
    
 0.933
PIK3R2
Uncharacterized protein.
    
 0.933
STAT5A
Signal transducer and activator of transcription.
   
 0.933
STAT5B
Signal transducer and activator of transcription.
   
 0.932
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.