CTBP2 protein (Canis lupus familiaris) - STRING interaction network

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Score

CTBP2

C-terminal binding protein 2. (914 aa)

Predicted Functional Partners:

RBBP8

0.982

TCF7L1

0.941

MECOM

0.937

TCF7

0.932

TCF7L2

0.919

RBPJ

0.918

RUNX1

0.913

HDAC1

0.907

HDAC2

0.876

PSAT1

0.868

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTBP2	HDAC1	ENSCAFP00000051395	ENSCAFP00000036819	C-terminal binding protein 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.907
CTBP2	HDAC2	ENSCAFP00000051395	ENSCAFP00000042408	C-terminal binding protein 2.	Histone deacetylase 2.	0.876
CTBP2	MECOM	ENSCAFP00000051395	ENSCAFP00000066483	C-terminal binding protein 2.	MDS1 and EVI1 complex locus.	0.937
CTBP2	PSAT1	ENSCAFP00000051395	ENSCAFP00000063891	C-terminal binding protein 2.	Phosphoserine aminotransferase.	0.868
CTBP2	RBBP8	ENSCAFP00000051395	ENSCAFP00000026919	C-terminal binding protein 2.	RB binding protein 8, endonuclease.	0.982
CTBP2	RBPJ	ENSCAFP00000051395	ENSCAFP00000064615	C-terminal binding protein 2.	Recombination signal binding protein for immunoglobulin kappa J region.	0.918
CTBP2	RUNX1	ENSCAFP00000051395	ENSCAFP00000014111	C-terminal binding protein 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.913
CTBP2	TCF7	ENSCAFP00000051395	ENSCAFP00000043629	C-terminal binding protein 2.	Transcription factor 7.	0.932
CTBP2	TCF7L1	ENSCAFP00000051395	ENSCAFP00000011603	C-terminal binding protein 2.	Transcription factor 7 like 1.	0.941
CTBP2	TCF7L2	ENSCAFP00000051395	ENSCAFP00000039879	C-terminal binding protein 2.	Transcription factor 7 like 2.	0.919
HDAC1	CTBP2	ENSCAFP00000036819	ENSCAFP00000051395	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	C-terminal binding protein 2.	0.907
HDAC1	HDAC2	ENSCAFP00000036819	ENSCAFP00000042408	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2.	0.958
HDAC1	MECOM	ENSCAFP00000036819	ENSCAFP00000066483	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	MDS1 and EVI1 complex locus.	0.914
HDAC1	RBPJ	ENSCAFP00000036819	ENSCAFP00000064615	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Recombination signal binding protein for immunoglobulin kappa J region.	0.932
HDAC1	RUNX1	ENSCAFP00000036819	ENSCAFP00000014111	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.923
HDAC1	TCF7	ENSCAFP00000036819	ENSCAFP00000043629	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Transcription factor 7.	0.588
HDAC1	TCF7L1	ENSCAFP00000036819	ENSCAFP00000011603	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Transcription factor 7 like 1.	0.595
HDAC1	TCF7L2	ENSCAFP00000036819	ENSCAFP00000039879	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Transcription factor 7 like 2.	0.647
HDAC2	CTBP2	ENSCAFP00000042408	ENSCAFP00000051395	Histone deacetylase 2.	C-terminal binding protein 2.	0.876
HDAC2	HDAC1	ENSCAFP00000042408	ENSCAFP00000036819	Histone deacetylase 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.958