STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX11DEAD/H-box helicase 11. (1044 aa)    
Predicted Functional Partners:
SYMPK
Symplekin.
   
   0.932
TIMELESS
Timeless circadian regulator.
   
  
 0.897
CHTF18
Chromosome transmission fidelity factor 18.
   
 
 0.846
RAD21
RAD21 cohesin complex component.
   
 
 0.816
NIPBL
Nipped-B protein.
    
 
 0.813
KLHL42
Kelch like family member 42.
      
 0.809
CCDC91
Coiled-coil domain containing 91.
    
 
 0.808
TIPIN
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
  
 0.801
ESCO2
Establishment of sister chromatid cohesion N-acetyltransferase 2.
   
 
 0.796
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
   
 
 0.769
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.