STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DRAXINDorsal inhibitory axon guidance protein. (366 aa)    
Predicted Functional Partners:
COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).
      
 0.875
RNF10
Ring finger protein 10.
      
 0.875
BICDL1
BICD family like cargo adaptor 1.
      
 0.852
SPICE1
Spindle and centriole associated protein 1.
   
    0.805
ARHGAP22
Rho GTPase activating protein 22.
      
 0.788
DCC
DCC netrin 1 receptor.
    
 
 0.785
PDE7B
Phosphodiesterase.
      
 0.769
NTN1
Netrin 1.
    
 
 0.760
NEO1
Neogenin 1.
    
 
 0.735
PMFBP1
Polyamine modulated factor 1 binding protein 1.
      
 0.702
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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