STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (265 aa)    
Predicted Functional Partners:
VPS36
Vacuolar protein sorting 36 homolog.
   
 
 0.912
CHMP6
Charged multivesicular body protein 6.
   
 
 0.835
PHOSPHO1
Phosphoethanolamine/phosphocholine phosphatase.
   
  
 0.807
UBE2Z
Ubiquitin conjugating enzyme E2 Z.
    
 
 0.747
CALCOCO2
Calcium binding and coiled-coil domain 2.
   
  
 0.736
BUD23
BUD23 rRNA methyltransferase and ribosome maturation factor.
 
 
   0.734
ELL
Elongation factor for RNA polymerase II.
   
 
 0.726
SPPL3
Signal peptide peptidase like 3.
   
  
 0.717
C9H17orf75
Chromosome 9 C17orf75 homolog.
    
 
 0.707
JMJD8
Jumonji domain containing 8.
 
      0.684
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.