STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHOT2WD repeat domain 90. (2322 aa)    
Predicted Functional Partners:
EFHB
EF-hand domain family member B.
    
   0.972
PACRG
Parkin coregulated.
   
 
 0.934
PACRGL
Parkin coregulated like.
   
 
 0.934
EFHC1
EF-hand domain containing 1.
    
 
 0.919
EFHC2
EF-hand domain containing 2.
   
 
 0.919
HABP2
Hyaluronan binding protein 2.
   
 
 0.901
HGFAC
Hepatocyte growth factor activator short chain; Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form; Belongs to the peptidase S1 family.
   
 
 0.901
F12
Coagulation factor XII.
   
 
 0.901
C2H1orf158
Chromosome 2 C1orf158 homolog.
    
   0.858
C6H1orf194
Chromosome 6 C1orf194 homolog.
    
   0.858
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.