STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRAMD1AGRAM domain containing 1A. (826 aa)    
Predicted Functional Partners:
TTC37
Tetratricopeptide repeat domain 37.
      
 0.825
ETV2
ETS variant 2.
   
  
 0.762
SCN1B
Sodium channel subunit beta-1; Regulatory subunit of multiple voltage-gated sodium channel complexes that play important roles in excitable membranes in brain, heart and skeletal muscle. Enhances the presence of the pore-forming alpha subunit at the cell surface and modulates channel gating characteristics and the rate of channel inactivation. Modulates the activity of a variety of pore-forming alpha subunits, such as SCN1A, SCN2A, SCN3A, SCN4A, SCN5A and SCN10A.
 
 
  
 0.680
PSMC4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
   
  
 0.667
PCTP
Phosphatidylcholine transfer protein.
      
 0.610
TPCN1
Two pore segment channel 1.
   
 
 0.522
TRAPPC11
Trafficking protein particle complex 11.
      
 0.512
AADAC
Arylacetamide deacetylase.
      
 0.511
GOLPH3
Golgi phosphoprotein 3.
      
 0.499
J9NY92_CANLF
Uncharacterized protein.
      
 0.485
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.