STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPRIN2G protein regulated inducer of neurite outgrowth 2. (500 aa)    
Predicted Functional Partners:
H2BFWT
Histone domain-containing protein; Belongs to the histone H2B family.
      
 0.875
SLC48A1
Solute carrier family 48 member 1.
      
 0.789
ORAI1
ORAI calcium release-activated calcium modulator 1.
   
  
 0.693
SETD7
SET domain containing 7, histone lysine methyltransferase.
   
  
 0.593
PLCZ1
Phosphoinositide phospholipase C.
   
  
 0.584
TSNAXIP1
Translin associated factor X interacting protein 1.
   
  
 0.525
SPEF1
Sperm flagellar 1.
      
 0.515
TENM4
Teneurin transmembrane protein 4.
      
 0.515
EYA2
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
      
 0.515
GRIN2B
Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (By similarity). In concert with DAPK1 at extrasynaptic sites, acts as a central mediator fo [...]
   
  
 0.513
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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