STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLK4Kallikrein related peptidase 4; Belongs to the peptidase S1 family. (267 aa)    
Predicted Functional Partners:
ENAM
Enamelin.
   
  
 0.908
AMBN
Ameloblastin.
   
 
 0.897
MMP20
Matrix metallopeptidase 20.
   
 
 0.894
AMELX
Amelogenin X isoform.
   
  
 0.848
AMTN
Amelotin.
   
  
 0.845
ODAM
Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface; Belongs to the ODAM family.
   
  
 0.796
WDR72
WD repeat domain 72.
   
  
 0.796
FAM83H
Family with sequence similarity 83 member H.
      
 0.707
TTC16
Tetratricopeptide repeat domain 16.
    
 
 0.690
ODAPH
Uncharacterized protein.
      
 0.643
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.