STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NTRK1Tyrosine-protein kinase receptor. (903 aa)    
Predicted Functional Partners:
NGF
Nerve growth factor; Belongs to the NGF-beta family.
   
 0.980
IRS2
Insulin receptor substrate 2.
    
 0.851
NTF4
Neurotrophin 4; Belongs to the NGF-beta family.
   
 
 0.706
NGFR
Nerve growth factor receptor.
   
 
 0.676
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.676
FRS2
Fibroblast growth factor receptor substrate 2.
   
 0.674
NTF3
Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family.
    
 
 0.622
CDH26
Cadherin 26.
   
 
 0.581
FBXL7
F-box and leucine rich repeat protein 7.
   
 
 0.578
CAPN14
Calpain 14; Belongs to the peptidase C2 family.
    
 
 0.571
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.