STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTC1Actin alpha cardiac muscle 1. (447 aa)    
Predicted Functional Partners:
MYH6
Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.748
TNNT2
Troponin T2, cardiac type.
   
 
 0.737
MYL3
Myosin light chain 3.
   
 
 0.695
MYL2
Myosin light chain 2.
   
 
 0.681
TPM1
Tropomyosin 1; Belongs to the tropomyosin family.
   
 
 0.627
CSRP3
Cysteine and glycine rich protein 3.
   
 
 0.604
ACTN2
Actinin alpha 2.
   
 
 0.599
TNNI3
Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
   
 
 0.591
SPATA17
Spermatogenesis associated 17.
    
 
 0.579
MYBPC3
Myosin binding protein C, cardiac.
   
 
 0.578
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.