STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (1111 aa)    
Predicted Functional Partners:
GRIK3
Glutamate ionotropic receptor kainate type subunit 3.
  
0.828
GRIK1
Glutamate ionotropic receptor kainate type subunit 1.
  
0.803
GRIK2
Glutamate ionotropic receptor kainate type subunit 2.
  
0.802
GRM4
Glutamate metabotropic receptor 4.
   
  
 0.797
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.637
DLG1
Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.
   
 0.627
ARL10
ADP ribosylation factor like GTPase 10.
      
 0.571
DLG3
Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.
   
 0.571
TENT4A
Terminal nucleotidyltransferase 4A.
      
 0.563
AARS1
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.
      
 0.529
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.