STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRX6Iroquois homeobox 6. (512 aa)    
Predicted Functional Partners:
ADIPOQ
Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.
   
  
 0.680
EIF4A1
Uncharacterized protein; Belongs to the DEAD box helicase family.
      
 0.679
DGKK
Diacylglycerol kinase.
      
 0.586
MYRF
Myelin regulatory factor.
      
 0.559
HOXB6
Homeobox B6.
   
 
 0.527
LOC475957
Uncharacterized protein.
      
 0.524
PPA1
Uncharacterized protein.
   
  
 0.507
CNMD
Chondromodulin.
   
  
 0.506
STARD3
StAR related lipid transfer domain containing 3.
      
 0.505
HAAO
3-hydroxyanthranilate 3,4-dioxygenase.
      
 0.495
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.