STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM63ATransmembrane protein 63A. (789 aa)    
Predicted Functional Partners:
TMEM147
Transmembrane protein 147.
   
  
 0.846
GALM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
   
  
 0.820
ZNF157
Zinc finger protein 157.
      
 0.816
FXYD3
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
   
  
 0.787
TMEM87A
Transmembrane protein 87A.
   
  
 0.738
ZDHHC9
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
 
 0.699
PPP1R1B
Protein phosphatase 1 regulatory inhibitor subunit 1B.
   
  
 0.677
SCNN1A
Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
  
 0.658
PRSS8
Serine protease 8; Belongs to the peptidase S1 family.
   
  
 0.645
GNB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
  
 0.595
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.