STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNT2Cyclin T2; Belongs to the cyclin family. (745 aa)    
Predicted Functional Partners:
CDK9
Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.
   
 0.999
AFF4
AF4/FMR2 family member 4.
   
 0.941
CCNT1
Cyclin T1; Belongs to the cyclin family.
    
0.937
CDK12
Cyclin dependent kinase 12.
   
 0.867
CDK7
Cyclin dependent kinase 7.
   
 
 0.864
CCNH
Cyclin H; Belongs to the cyclin family.
   
  
 0.855
GTF2B
General transcription factor IIB.
   
 
 0.854
NELFE
Negative elongation factor complex member E.
   
 0.837
GTF2F1
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
   
 0.826
ELL
Elongation factor for RNA polymerase II.
    
 0.787
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.