MPV17L2 protein (Canis lupus familiaris) - STRING interaction network

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Known Interactions

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Predicted Interactions

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MPV17L2

MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (335 aa)

Predicted Functional Partners:

MPV17L

0.909

MRPS18B

0.743

METTL15

0.709

MUL1

0.685

C7H18orf32

0.677

MAF1

0.677

NUP210

0.676

MRPS22

0.636

MRPL45

0.636

F6UMJ5_CANLF

0.636

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C7H18orf32	MPV17L2	ENSCAFP00000039333	ENSCAFP00000053311	Chromosome 7 C18orf32 homolog.	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.677
C7H18orf32	MUL1	ENSCAFP00000039333	ENSCAFP00000022194	Chromosome 7 C18orf32 homolog.	Mitochondrial E3 ubiquitin protein ligase 1.	0.515
C7H18orf32	NUP210	ENSCAFP00000039333	ENSCAFP00000036016	Chromosome 7 C18orf32 homolog.	Nucleoporin 210.	0.493
F6UMJ5_CANLF	MPV17L2	ENSCAFP00000032255	ENSCAFP00000053311	Tim44 domain-containing protein.	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.636
F6UMJ5_CANLF	MRPS18B	ENSCAFP00000032255	ENSCAFP00000000593	Tim44 domain-containing protein.	Mitochondrial ribosomal protein S18B.	0.872
F6UMJ5_CANLF	MRPS22	ENSCAFP00000032255	ENSCAFP00000011280	Tim44 domain-containing protein.	Uncharacterized protein.	0.817
MAF1	METTL15	ENSCAFP00000064398	ENSCAFP00000015077	Repressor of RNA polymerase III transcription MAF1; Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family.	Methyltransferase like 15.	0.679
MAF1	MPV17L2	ENSCAFP00000064398	ENSCAFP00000053311	Repressor of RNA polymerase III transcription MAF1; Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family.	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.677
METTL15	MAF1	ENSCAFP00000015077	ENSCAFP00000064398	Methyltransferase like 15.	Repressor of RNA polymerase III transcription MAF1; Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family.	0.679
METTL15	MPV17L2	ENSCAFP00000015077	ENSCAFP00000053311	Methyltransferase like 15.	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.709
METTL15	MRPS18B	ENSCAFP00000015077	ENSCAFP00000000593	Methyltransferase like 15.	Mitochondrial ribosomal protein S18B.	0.712
METTL15	MRPS22	ENSCAFP00000015077	ENSCAFP00000011280	Methyltransferase like 15.	Uncharacterized protein.	0.577
MPV17L	MPV17L2	ENSCAFP00000039067	ENSCAFP00000053311	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family.	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.909
MPV17L2	C7H18orf32	ENSCAFP00000053311	ENSCAFP00000039333	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	Chromosome 7 C18orf32 homolog.	0.677
MPV17L2	F6UMJ5_CANLF	ENSCAFP00000053311	ENSCAFP00000032255	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	Tim44 domain-containing protein.	0.636
MPV17L2	MAF1	ENSCAFP00000053311	ENSCAFP00000064398	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	Repressor of RNA polymerase III transcription MAF1; Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family.	0.677
MPV17L2	METTL15	ENSCAFP00000053311	ENSCAFP00000015077	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	Methyltransferase like 15.	0.709
MPV17L2	MPV17L	ENSCAFP00000053311	ENSCAFP00000039067	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.909
MPV17L2	MRPL45	ENSCAFP00000053311	ENSCAFP00000024480	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	Tim44 domain-containing protein.	0.636
MPV17L2	MRPS18B	ENSCAFP00000053311	ENSCAFP00000000593	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	Mitochondrial ribosomal protein S18B.	0.743

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Network Stats

number of nodes:

11

number of edges:

44

average node degree:

8

avg. local clustering coefficient:

0.825

expected number of edges:

10

PPI enrichment p-value:

9.21e-15

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009058

Biosynthetic process

9 of 320

0.57

0.35

0.0380

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 482

0.48

0.4

0.00045

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:993

Peptidoglycan synthesis, and Cell division site

4 of 18

1.47

1.08

0.0035

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00473

D-Alanine metabolism

4 of 4

2.12

2.46

1.11e-05

map01502

Vancomycin resistance

3 of 6

1.82

1.42

0.0012

map00290

Valine, leucine and isoleucine biosynthesis

2 of 2

2.12

1.14

0.0071

map01210

2-Oxocarboxylic acid metabolism

2 of 5

1.72

0.89

0.0174

map00550

Peptidoglycan biosynthesis

3 of 25

1.2

0.72

0.0174

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0573

Peptidoglycan synthesis

3 of 12

1.52

0.8

0.0214

KW-0961

Cell wall biogenesis/degradation

3 of 13

1.48

0.79

0.0214

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