STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCML2Scm polycomb group protein like 2. (726 aa)    
Predicted Functional Partners:
CCDC15
Coiled-coil domain containing 15.
      
 0.804
PGM2L1
Phosphoglucomutase 2 like 1.
   
  
 0.712
TEX101
Testis expressed 101.
      
 0.707
CBX8
Chromobox 8.
   
 
 0.678
IER5L
Immediate early response 5 like.
      
 0.656
SH2D4A
SH2 domain containing 4A.
      
 0.628
HORMAD2
HORMA domain-containing protein 2; Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid- pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break- independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for norm [...]
   
  
 0.592
ANKRD34C
Ankyrin repeat domain 34C.
   
 
 0.577
ASZ1
Ankyrin repeat, SAM and basic leucine zipper domain containing 1.
   
 
 0.576
YOD1
YOD1 deubiquitinase.
      
 0.570
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.