STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD276CD276 molecule. (680 aa)    
Predicted Functional Partners:
VSIR
V-set immunoregulatory receptor.
      
 0.646
CNNM3
Cyclin and CBS domain divalent metal cation transport mediator 4.
   
  
 0.626
TNFRSF14
TNF receptor superfamily member 14.
    
 
 0.572
ANO6
Anoctamin.
      
 0.560
CTLA4
Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
      
 0.545
SLC39A14
Solute carrier family 39 member 14.
   
  
 0.538
CD80
CD80 molecule.
    
 
0.537
CD48
CD48 molecule.
   
  
 0.522
SLC4A7
Anion exchange protein.
   
  
 0.520
CPNE3
Copine 3.
   
  
 0.517
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.