STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MBNL1Muscleblind like splicing regulator 1. (436 aa)    
Predicted Functional Partners:
CELF1
CUGBP Elav-like family member 1.
   
 
 0.764
CLCN1
Chloride channel protein 1; Voltage-gated chloride channel. Plays an important role in membrane repolarization in skeletal muscle cells after muscle contraction.
      
 0.750
PRSS53
Serine protease 53; Belongs to the peptidase S1 family.
    
 
 0.731
DMPK
DM1 protein kinase.
   
  
 0.709
TIAL1
TIA1 cytotoxic granule associated RNA binding protein like 1.
   
 
 0.701
RBFOX2
RNA binding fox-1 homolog 2.
    
 
 0.664
INSR
Tyrosine-protein kinase receptor.
   
  
 0.663
RBFOX1
RNA binding fox-1 homolog 1.
    
 
 0.633
SORBS1
Sorbin and SH3 domain containing 1.
   
  
 0.626
NOVA2
NOVA alternative splicing regulator 2.
      
 0.611
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.