STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (1040 aa)    
Predicted Functional Partners:
RSPO1
R-spondin 1.
   
 0.997
RSPO2
R-spondin 2.
   
 0.995
RSPO3
R-spondin 3.
   
 0.974
RNF43
Ring finger protein 43.
   
 0.971
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
  
0.931
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
  
0.925
RSPO4
R-spondin 4.
   
 0.909
ZNRF3
Zinc and ring finger 3.
   
 0.875
ADGRL2
Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.708
ADGRL1
Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.708
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.