GGA1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GGA1

Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (678 aa)

Predicted Functional Partners:

GGA2

0.964

GGA3

0.960

RABEP1

0.946

IGF2R

0.934

SORL1

0.914

CCDC91

0.906

BACE1

0.885

SORT1

0.774

AP1M1

0.730

WDR48

0.688

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1M1	GGA1	ENSCAFP00000023182	ENSCAFP00000053910	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	0.730
AP1M1	GGA2	ENSCAFP00000023182	ENSCAFP00000031044	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	Golgi associated, gamma adaptin ear containing, ARF binding protein 2.	0.683
AP1M1	GGA3	ENSCAFP00000023182	ENSCAFP00000007064	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	Golgi associated, gamma adaptin ear containing, ARF binding protein 3.	0.523
AP1M1	IGF2R	ENSCAFP00000023182	ENSCAFP00000036713	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein.	0.520
AP1M1	SORT1	ENSCAFP00000023182	ENSCAFP00000048566	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	Sortilin.	0.631
BACE1	GGA1	ENSCAFP00000019275	ENSCAFP00000053910	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	0.885
BACE1	GGA2	ENSCAFP00000019275	ENSCAFP00000031044	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Golgi associated, gamma adaptin ear containing, ARF binding protein 2.	0.645
BACE1	GGA3	ENSCAFP00000019275	ENSCAFP00000007064	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Golgi associated, gamma adaptin ear containing, ARF binding protein 3.	0.496
BACE1	SORL1	ENSCAFP00000019275	ENSCAFP00000017344	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Sortilin related receptor 1.	0.493
BACE1	SORT1	ENSCAFP00000019275	ENSCAFP00000048566	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Sortilin.	0.668
CCDC91	GGA1	ENSCAFP00000050457	ENSCAFP00000053910	Coiled-coil domain containing 91.	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	0.906
CCDC91	GGA2	ENSCAFP00000050457	ENSCAFP00000031044	Coiled-coil domain containing 91.	Golgi associated, gamma adaptin ear containing, ARF binding protein 2.	0.647
GGA1	AP1M1	ENSCAFP00000053910	ENSCAFP00000023182	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.730
GGA1	BACE1	ENSCAFP00000053910	ENSCAFP00000019275	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.885
GGA1	CCDC91	ENSCAFP00000053910	ENSCAFP00000050457	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Coiled-coil domain containing 91.	0.906
GGA1	GGA2	ENSCAFP00000053910	ENSCAFP00000031044	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Golgi associated, gamma adaptin ear containing, ARF binding protein 2.	0.964
GGA1	GGA3	ENSCAFP00000053910	ENSCAFP00000007064	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Golgi associated, gamma adaptin ear containing, ARF binding protein 3.	0.960
GGA1	IGF2R	ENSCAFP00000053910	ENSCAFP00000036713	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein.	0.934
GGA1	RABEP1	ENSCAFP00000053910	ENSCAFP00000022927	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Rabaptin, RAB GTPase binding effector protein 1.	0.946
GGA1	SORL1	ENSCAFP00000053910	ENSCAFP00000017344	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Sortilin related receptor 1.	0.914