STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDS5AUncharacterized protein. (1367 aa)    
Predicted Functional Partners:
SMC1A
Structural maintenance of chromosomes protein.
   
 0.976
WAPL
WAPL cohesin release factor.
   
 0.975
STAG2
Stromal antigen 2.
   
 0.972
SMC3
Structural maintenance of chromosomes protein.
   
 0.959
NIPBL
Nipped-B protein.
   
 0.957
RAD21
RAD21 cohesin complex component.
   
 0.940
CDCA5
Cell division cycle associated 5.
   
 0.902
STAG1
Stromal antigen 1.
   
 0.900
PDS5B
PDS5 cohesin associated factor B.
  
0.856
ESCO2
Establishment of sister chromatid cohesion N-acetyltransferase 2.
   
 0.850
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.