ERGIC2 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ERGIC2

ERGIC and golgi 2. (391 aa)

Predicted Functional Partners:

ERGIC3

0.975

GTPBP3

0.937

DERL2

0.831

DERL3

0.827

CCDC61

0.827

ZNF382

0.819

TRMU

0.790

ZNF461

0.789

SEL1L

0.726

SEL1L2

0.718

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC61	ERGIC2	ENSCAFP00000048520	ENSCAFP00000054185	Coiled-coil domain containing 61.	ERGIC and golgi 2.	0.827
CCDC61	ZNF382	ENSCAFP00000048520	ENSCAFP00000039188	Coiled-coil domain containing 61.	Zinc finger protein 382.	0.777
CCDC61	ZNF461	ENSCAFP00000048520	ENSCAFP00000035898	Coiled-coil domain containing 61.	Zinc finger protein 461.	0.806
DERL2	DERL3	ENSCAFP00000055568	ENSCAFP00000020782	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.941
DERL2	ERGIC2	ENSCAFP00000055568	ENSCAFP00000054185	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	ERGIC and golgi 2.	0.831
DERL2	SEL1L	ENSCAFP00000055568	ENSCAFP00000056064	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.988
DERL2	SEL1L2	ENSCAFP00000055568	ENSCAFP00000058448	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L2 adaptor subunit of ERAD E3 ligase.	0.698
DERL3	DERL2	ENSCAFP00000020782	ENSCAFP00000055568	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.941
DERL3	ERGIC2	ENSCAFP00000020782	ENSCAFP00000054185	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	ERGIC and golgi 2.	0.827
DERL3	SEL1L	ENSCAFP00000020782	ENSCAFP00000056064	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.937
DERL3	SEL1L2	ENSCAFP00000020782	ENSCAFP00000058448	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L2 adaptor subunit of ERAD E3 ligase.	0.698
ERGIC2	CCDC61	ENSCAFP00000054185	ENSCAFP00000048520	ERGIC and golgi 2.	Coiled-coil domain containing 61.	0.827
ERGIC2	DERL2	ENSCAFP00000054185	ENSCAFP00000055568	ERGIC and golgi 2.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.831
ERGIC2	DERL3	ENSCAFP00000054185	ENSCAFP00000020782	ERGIC and golgi 2.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.827
ERGIC2	ERGIC3	ENSCAFP00000054185	ENSCAFP00000011961	ERGIC and golgi 2.	ERGIC and golgi 3.	0.975
ERGIC2	GTPBP3	ENSCAFP00000054185	ENSCAFP00000022668	ERGIC and golgi 2.	GTP binding protein 3, mitochondrial.	0.937
ERGIC2	SEL1L	ENSCAFP00000054185	ENSCAFP00000056064	ERGIC and golgi 2.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.726
ERGIC2	SEL1L2	ENSCAFP00000054185	ENSCAFP00000058448	ERGIC and golgi 2.	SEL1L2 adaptor subunit of ERAD E3 ligase.	0.718
ERGIC2	TRMU	ENSCAFP00000054185	ENSCAFP00000063762	ERGIC and golgi 2.	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase.	0.790
ERGIC2	ZNF382	ENSCAFP00000054185	ENSCAFP00000039188	ERGIC and golgi 2.	Zinc finger protein 382.	0.819