STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPIBactericidal permeability increasing protein. (593 aa)    
Predicted Functional Partners:
LBP
Lipopolysaccharide binding protein.
  
 
0.775
RPS19
Uncharacterized protein.
      
 0.648
H1-5
Histone cluster 1 H1 family member b.
      
 0.564
CTSG
Granzyme B; Belongs to the peptidase S1 family.
   
  
 0.549
DLA-DMA
MHC class II antigen DM alpha; Belongs to the MHC class II family.
   
  
 0.505
DLA-DRA
Ig-like domain-containing protein; Belongs to the MHC class II family.
   
  
 0.488
C1QA
Complement C1q A chain.
   
  
 0.472
MPO
Myeloperoxidase.
   
  
 0.469
A2ML1
Alpha-2-macroglobulin like 1.
   
  
 0.465
ZP2
Processed zona pellucida sperm-binding protein 2; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor.
      
 0.455
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.