STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R3HDM1R3H domain containing 1. (1137 aa)    
Predicted Functional Partners:
MAPK7
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
  
 0.694
ZRANB3
Zinc finger RANBP2-type containing 3.
   
 
 0.679
LEMD3
LEM domain containing 3.
   
 
 0.627
CDHR4
Cadherin related family member 4.
      
 0.620
ABCG2
ATP binding cassette subfamily G member 2.
   
  
 0.615
GHR
Growth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity).
   
  
 0.594
CNGB1
Cyclic nucleotide gated channel subunit beta 1.
      
 0.592
SPOCK1
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1.
      
 0.578
XKR4
XK-related protein.
      
 0.577
SAR1B
Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family.
   
  
 0.569
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.