STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRN2Protein tyrosine phosphatase receptor type N2. (1061 aa)    
Predicted Functional Partners:
PTPRN
Protein tyrosine phosphatase receptor type N.
  
 
0.916
ESYT2
Extended synaptotagmin 2.
   
  
 0.874
CPAMD8
C3 and PZP like alpha-2-macroglobulin domain containing 8.
   
 
 0.811
WDR60
WD repeat domain 60.
    
 
 0.809
INSIG1
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
   
  
 0.622
PCSK2
Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.
   
  
 0.618
USP16
Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
      
 0.609
RWDD2B
RWD domain-containing protein.
   
  
 0.609
PHTF1
Putative homeodomain transcription factor 1.
    
 
 0.596
CELF4
RRM domain-containing protein.
   
  
 0.567
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.