STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
 0.885
PCED1A
PC-esterase domain containing 1A.
      
 0.791
POF1B
POF1B actin binding protein.
      
 0.740
RNF24
Ring finger protein 24.
   
 
 0.739
ZNF711
Zinc finger protein 711.
    
 
 0.736
PEX11B
Peroxisomal biogenesis factor 11 beta.
   
  
 0.728
VPS16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
      
 0.720
RFTN1
Raftlin, lipid raft linker 1.
      
 0.679
ZFP37
ZFP37 zinc finger protein.
    
 
 0.679
FYN
Tyrosine-protein kinase.
   
 0.596
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.