STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E2F7E2F transcription factor 7. (913 aa)    
Predicted Functional Partners:
E2F8
E2F transcription factor 8.
  
0.953
DDIAS
DNA damage induced apoptosis suppressor.
   
  
 0.728
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
  
 0.632
E2F6
E2F transcription factor 6.
   
 
0.593
NOP14
NOP14 nucleolar protein.
   
  
 0.592
E2F4
E2F transcription factor 4.
   
 
0.579
PSRC1
Proline and serine rich coiled-coil 1.
      
 0.573
KDM7A
Lysine demethylase 7A.
      
 0.566
SNAPC3
Small nuclear RNA activating complex polypeptide 3.
   
  
 0.561
POU6F1
POU domain protein.
   
  
 0.561
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.