STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FXYD3FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (117 aa)    
Predicted Functional Partners:
TMEM63A
Transmembrane protein 63A.
   
  
 0.787
FXYD5
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
      
 0.732
FXYD2
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
      
 0.717
ATP1A4
Sodium/potassium-transporting ATPase subunit alpha.
    
 0.617
ATP1A3
ATPase Na+/K+ transporting subunit alpha 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
    
 0.617
FXYD6
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
  
   
0.582
ATP1B3
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
   
 0.577
ATP1B2
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
    
 0.575
SCNN1A
Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
  
 0.567
ENSCAFP00000057785
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
      
 0.563
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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