STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S100A1Protein S100; Belongs to the S-100 family. (94 aa)    
Predicted Functional Partners:
S100B
Protein S100; Belongs to the S-100 family.
    
 
0.807
ECRG4
ECRG4 augurin precursor.
   
  
 0.668
GMFG
Glia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily.
   
 
 0.648
S100A2
Protein S100; Belongs to the S-100 family.
    
 
0.610
S100A5
Protein S100-A4.
   
 
0.584
SRI
Sorcin.
   
  
 0.567
CRLF1
Cytokine receptor like factor 1.
      
 0.560
S100A16
Protein S100; Belongs to the S-100 family.
   
 
0.533
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
   
  0.532
CLDN7
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
   
 0.517
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.