STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JDP2Jun dimerization protein 2. (358 aa)    
Predicted Functional Partners:
BATF3
Basic leucine zipper ATF-like transcription factor 3.
   
0.925
BATF2
Basic leucine zipper ATF-like transcription factor 2.
   
 
0.918
JUNB
JunB proto-oncogene, AP-1 transcription factor subunit.
   
 
 0.879
IRF4
Interferon regulatory factor 4.
   
 
 0.837
CXCR5
C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.
      
 0.709
JUND
JunD proto-oncogene, AP-1 transcription factor subunit.
   
 
 0.683
BACH2
BTB domain and CNC homolog 2.
   
 
 0.676
IRF8
Interferon regulatory factor 8.
   
 
 0.641
STAT3
Signal transducer and activator of transcription.
   
 
 0.610
ICOS
Inducible T-cell costimulator; Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin- 2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40- mediated class switching o [...]
   
  
 0.593
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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